Which statement is not true regarding topical corticosteroids?

The statement regarding topical corticosteroids is that they should be applied thickly is not true. Topical corticosteroids are designed to be effective when applied in a thin layer to the affected area of the skin. Applying them too thickly does not enhance their therapeutic effect and can lead to increased side effects, such as skin irritation or systemic absorption, particularly with higher-potency formulations.

In contrast, applying a thin layer ensures that the medication can adequately penetrate the skin to exert its anti-inflammatory effects while minimizing the risk of adverse reactions, such as skin thinning or atrophy, which is a known side effect of corticosteroid use. The other statements highlight the appropriate uses and characteristics of corticosteroids, emphasizing their role in treating inflammation and the potential side effects that can arise from improper application practices.