Which statement about sildenafil (Viagra) is true?

Sildenafil, commonly known by its brand name Viagra, is primarily indicated for the treatment of erectile dysfunction. The correct statement emphasizes that sildenafil should be taken as needed, typically one hour before sexual activity, and is not intended for daily use. This aligns with the pharmacokinetics of the drug, where it starts to work about 30 to 60 minutes after ingestion, providing a window for sexual activity.

It's important to note that sildenafil is not designed for continuous daily administration unless specifically prescribed for conditions like pulmonary arterial hypertension and should not be taken twice daily without medical guidance. Moreover, the initial purpose of sildenafil was not related to diabetes; it was originally developed to treat pulmonary hypertension before its effectiveness for erectile dysfunction was discovered.

Additionally, caution is advised for men who are taking nitrates concurrently with sildenafil due to the risk of significant hypotension, which can lead to serious cardiovascular complications. Therefore, the correct interpretation pertaining to sildenafil's usage aligns with its prescribed guidelines and safety considerations in context with other medications, particularly nitrates. This knowledge is crucial for safe and effective management in clinical situations.