Which of the following is true about ophthalmic anti-inflammatory and antiinfective agents?

The statement regarding antibiotics being administered locally to prevent drug resistance is accurate. When it comes to the treatment of eye infections, using topical antibiotics allows for higher concentrations of the drug to be applied directly to the site of infection, which can effectively combat pathogens while minimizing systemic absorption. This localized treatment reduces the potential for systemic side effects and may help in limiting the development of antibiotic resistance because it ensures that the medication is specifically targeting the infection without affecting the entire body's flora.

When antibiotics are used systemically, they may not only treat the infection but can also disturb the balance of microbial flora, leading to resistance over time. Administering them topically focuses the treatment where it's needed most, providing a more strategic approach to managing infections while reducing the risk of widespread resistance, which is a critical consideration in pharmacology.

The other statements lack the same level of accuracy regarding the treatment of ophthalmic conditions. The effectiveness of treatment can be influenced by the condition of the mucous membranes, especially if they are compromised. The treatment of viral infections typically involves both eyes, as viruses can spread quickly, making unilateral treatment insufficient. Lastly, while some topical medications may be similar, they are not always interchangeable due to differences in formulation, concentration, and specific pharmacokinetic properties