Which is true concerning oral antifungals?

The statement that oral antifungals bind to the oral mucosa and remain effective for up to 3 hours is accurate. This characteristic is particularly relevant for certain formulations of antifungals, such as those that can adhere to oral tissues and exert a local therapeutic effect. By binding to the mucosal surfaces, these drugs can enhance their antifungal activity in the oral cavity, which can be particularly beneficial in treating localized infections such as oral thrush.

In various clinical settings, maintaining contact with the affected site can lead to improved efficacy in the treatment of fungal infections. This effect can help ensure that the medication is available at the site of infection for a prolonged period, enhancing the overall effectiveness of the treatment.

Other options detail incorrect or incomplete information regarding oral antifungals. They do not universally treat all fungal infections, nor are they always deemed safe for small children, as many antifungal medications come with specific dosing recommendations and safety profiles. Moreover, oral antifungal medications do not require chewing for effectiveness; they are typically swallowed whole to ensure proper systemic absorption.