Which characteristic is NOT true of sulfonylureas?

Sulfonylureas are a class of oral hypoglycemic agents that primarily function by stimulating the pancreas to release insulin. While they enhance insulin secretion, they are not insulin-like preparations themselves; rather, they act on the beta cells of the pancreas to increase insulin production. This distinction is crucial because it highlights that sulfonylureas rely on the pancreas to produce insulin rather than mimicking insulin directly.

In addition, sulfonylureas can lead to hypoglycemia, particularly in patients who are not eating enough, are under vigorous exercise, or use them in combination with other antidiabetic medications. This risk makes careful monitoring essential when using these agents.

Moreover, sulfonylureas exhibit a range of pharmacokinetics, meaning that different types within this class can have varying times of onset and durations of action. This variability allows for tailoring treatment to individual patients based on their specific needs and insulin response, but it does not imply they are insulin or insulin preparations themselves. Understanding these characteristics is vital for effective diabetes management and medication use.