Which agent is known to rapidly diffuse through burns and effectively combat bacterial wound invasion?

Sulfamylon, known generically as mafenide acetate, is an antibacterial agent particularly effective in the treatment of burns. One of its key properties is its ability to rapidly diffuse through eschar, which is the dead tissue that forms at a burn site. This characteristic allows Sulfamylon to combat bacterial invasion effectively and efficiently prevent infections in compromised skin.

In the context of burn treatment, bacterial infection is a significant risk, and Sulfamylon's mechanism of action helps impede the growth of bacteria by inhibiting their ability to synthesize folic acid, an essential component for bacterial reproduction. Its formulation allows it to penetrate deeply into burn wounds, providing an effective barrier against pathogens.

The other agents listed have different uses and mechanisms. Neosporin is a topical antibiotic ointment but is generally more suited for minor cuts and scrapes rather than deep burns. Hydrocortisone is a corticosteroid primarily used to reduce inflammation and is not primarily an antibacterial agent. Bacitracin, while it has antibacterial properties, does not have the same level of efficacy in penetrating necrotic tissue as Sulfamylon does.

Thus, Sulfamylon's unique ability to diffuse through burn eschar rapidly and its effectiveness against bacterial infections make it the appropriate choice