What is NOT true about testosterone replacement therapy?

Testosterone replacement therapy (TRT) is a treatment tailored to individual needs, and this is reflected in the practice of determining appropriate treatment and dosage. The statement that treatment and dosage are the same for all males is not true because factors such as age, weight, underlying health conditions, and specific testosterone levels influence the dosage and administration method for each individual.

For example, younger men or those with specific conditions may require different doses compared to older men or those with varying health issues. This personalized approach ensures that patients receive the most effective and safest dosage, minimizing the risk of side effects and maximizing therapeutic benefits.

In contrast, the other options provide factual details about testosterone delivery methods. Androderm patches indeed need to be rotated to prevent irritation and ensure consistent absorption. Testoderm patches are specifically designed for application to the scrotum, which helps enhance absorption due to the skin's unique characteristics in that area. Additionally, transdermal patches, including many testosterone formulations, are often applied at night to mimic the natural circadian rhythm of testosterone production, optimizing its physiological effects.