Transdermal opioids are indicated for which duration of action?

Transdermal opioids are specifically designed to provide continuous systemic analgesia over an extended period. The correct duration of action for transdermal opioids, such as fentanyl patches, typically ranges from 24 to 72 hours. This extended release mechanism allows for steady absorption of the medication through the skin into the bloodstream, which helps maintain consistent pain control for patients who require long-term management of chronic pain.

This extended action is particularly beneficial for patients since it minimizes the need for multiple doses per day, enhances compliance, and reduces the risk of breakthrough pain episodes that can occur with shorter-acting opioids. Therefore, the 24 to 72 hours duration aligns with the therapeutic expectations from transdermal formulations, making it the correct choice.