Is it advisable to instill drugs directly on the cornea?

Instilling drugs directly on the cornea is generally not advisable due to the potential for damage to the delicate tissues of the eye. The cornea is a sensitive part of the eye that serves as a barrier and a protective layer, and applying substances directly to it can lead to irritation, abrasion, or other harmful effects.

Additionally, many medications are designed to be delivered in specific formulations that account for the unique environment of the eye, and direct instillation can circumvent those formulations' intended effects. It’s crucial to ensure that any drug application to the eye is done thoughtfully, using appropriate routes and methods to maintain eye health and avoid complications.

While certain medications may have specific indications for corneal application (usually under controlled conditions), such instances are exceptions rather than the standard practice, emphasizing the importance of caution in direct application to the cornea.